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Project publishable reports

Project Publishable SummaryAdobe Acrobat file (April 2021)


Project deliverables

Deliverable 1: New reference fields for dosimetry in electron beams with ultra-high pulse dose ratesAdobe Acrobat file (November 2021)


Peer-reviewed publications

25) A. Cimmino et al. Comparison of OSL and TL Dosemeters With Data Collected at the MT25 Cyclic Electron Accelerator, Radiation Protection Dosimetry, published 22 August 2022.

24) E. Lee et al. Ultrahigh dose rate pencil beam scanning proton dosimetry using ion chambers and a calorimeter in support of first in-human FLASH clinical trial, Medical Physics, published 2 July 2022.

23) C. Oancea et al. Radiation field measurements and simulations for therapeutic and FLASH proton beams using a Timepix3 detector: Dose rate, Flux and LET, Physica Medica, submitted.

22) J. Šolc et al. Monte Carlo Modelling of Pixel Clusters in Timepix Detectors Using the MCNP Code, Physica Medica, published 16 August 2022.

21) A. Bourgouin et al. Alanine absolute dose to water measurement in ultra-high pulse dose rates electron beam, Physics in Medicine and Biology, submitted.

20) A. Bourgouin et al. The probe-format graphite calorimeter, Aerrow, for absolute dosimetry in ultra-high pulse dose rate electron beams, Medical Physics, 1 August 2022.

19) G. V. Rinati et al. Application of a novel diamond detector for commissioning of FLASH radiotherapy electron beams, Medical Physics, 2 June 2022.

18) M. Cavallone et al. Determination of the ion collection efficiency of the Razor Nano Chamber for ultra-high dose-rate electron beams, Medical Physics, 20 April 2022.

17) F. Gómez et al. Development of an ultra-thin parallel plate ionization chamber for dosimetry in FLASH radiotherapy, Medical Physics, 13 April 2022.

16) A. Bourgouin et al. Characterization of the PTB ultra-high pulse dose rate reference electron beam, Physics in Medicine & Biology, accepted 8 April 2022.

15) R. Kranzer et al. Response of diamond detectors in ultra-high dose-per-pulse electron beams for dosimetry at FLASH radiotherapy, Physics in Medicine & Biology, 21 March 2022.

14) M. McManus et al. Determination of beam quality correction factors for the Roos plane-parallel ionisation chamber exposed to very high energy electron (VHEE) beams using Geant4, Physics in Medicine & Biology, 17 March 2022.

13) Patrik Gonçalves Jorge et al. Technical note: Validation of an ultrahigh dose rate pulsed electron beam monitoring system using a current transformer for FLASH preclinical studies, Medical Physics, 22 January 2022.

12) M. Marinelli et al. Design, realization, and characterization of a novel diamond detector prototype for FLASH radiotherapy dosimetry, Medical Physics, 21 January 2022.

11) C. Oancea et al. Stray radiation produced in FLASH electron beams characterized by the MiniPIX Timepix3 Flex detector, Journal of Instrumentation, 17 January 2022. Available also here.

10) M. McManus et al. A Geant4 Fano test for novel very high energy electron beams, Physics in Medicine and Biology, 22 December 2021.

9) R. Oesterle et al. Implementation and validation of a beam-current transformer on a medical pulsed electron beam LINAC for FLASH-RT beam monitoring, Journal of Applied Clinical Medical Physics, 5 October 2021.

8) P. Chaudhary et al. Radiobiology Experiments With Ultra-high Dose Rate Laser-Driven Protons: Methodology and State-of-the-Art, Frontiers in Physics, 8 April 2021.

7) D.Poppinga et al. VHEE beam dosimetry at CERN Linear Electron Accelerator for Research under ultra-high dose rate conditions, Biomedical Physics & Engineering Express, December 2020.

6) R.Kranzer et al. Ion collection efficiency of ionization chambers in ultra-high dose-per-pulse electron beams, Medical Physics, November 2020.

5) K. Kokurewicz et al. Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators, Frontiers in Physics, November 2020.

4) A. Schüller et al. The European Joint Research Project UHDpulse – Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates, Physica Medica, November 2020.

3) A. Bourgouin et al. Calorimeter for Real-Time Dosimetry of Pulsed Ultra-High Dose Rate Electron Beam, Frontiers in Physics, October 2020.

2) F. Romano et al. Challenges in dosimetry of particle beams with ultra-high pulse dose rates, Journal of Physics: Conference series, October 2020.

1) M. McManus et al. The challenge of ionisation chamber dosimetry in ultra-short pulsed high dose-rate Very High Energy Electron beams, Scientific Reports, June 2020.


Oral presentations

62) Investigation of Plastic Material Properties Exposed to Ultra-high Dose Rate Electron Beam (Y. C. Gedik), IUPESM 2022, June 2022. 2nd place in Best Young Presentation Award for 2022.

61) Characterization of The PTB Ultra-High Pulse Dose Rate Electron Beam (A. Bourgouin), IUPESM 2022, June 2022.

60) Dose, Flux and LET Measurements of Scattered Radiation in Proton Therapy Using Timepix3 Detectors (C. Oancea), PTCOG 60, June 2022.

59) Overview of the EMPIR project UHDpulse – “Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates” (A.Schüller), webinar of Associazione Italiana di Fisica Medica, 19 May 2022.

58) Metrologie pro radioterapii pulzními svazky s vysokou dávkou v pulzu (J. Šmoldasová), Konference radiologické fyziky, 21 April 2022.

57) Highlights from EMPIR JRP UHDpulse “Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates” (A. Schüller), EURAMET TC-IR meeting, 27 January 2022.

56) EMPIR UHDpulse progress (A.Subiel), TG359 meeting, October 2021.

55) New R&D platform with unique capabilities for electron FLASH and VHEE radiation therapy and radiation biology under preparation at PITZ (FLASHlab@PITZ) (F. Stephan), FRPT2021 conference, December 2021.

54) Spectral and Intensity Sensitive Characterization of Pulsed Flash Proton Fields With the Pixel Detector TimePIX3 (C.Oancea), FRPT2021 conference, December 2021.

53) Developments in Active Neutron Spectrometry for Neutron Stray Radiation Field Characterization in Flash Radiotherapy (M.Zboril), FRPT2021 conference, December 2021.

52) Overview and Current Status of the Joint Research Project UHDpulse – “Metrology for Advanced Radiotherapy Using Particle Beams With Ultra-High Pulse Dose Rates” (A.Schüller), FRPT2021 conference, December 2021.

51) Flash RT: Current Status of Dosimetry, QA, Challenges and the Need for Further Developments (A.Subiel), FRPT2021 conference, December 2021.

50) Flash Teaching Lecture: Dosimetry at Ultra-High Dose Rate and the Clinical Translation of the Procedures (C.Bailat), FRPT2021 conference, December 2021.

49) Laser-Driven Ion Beams and Ultra-High Dose Rate Radiobiology (M.Borghesi), FRPT2021 conference, December 2021.

48) Ultra Thin Plane-Parallel Ionization Chambers: Expanding the Range of Air Ionization Chambers Into Ultra-High Dose Rate (F.Gomez), FRPT2021 conference, December 2021.

47) Fricke Dosimetry as a Primary Standard and Reference for Absorbed Dose to Water in Ultra High Pulse Dose Rate Electron Beams (F.Frei), FRPT2021 conference, December 2021.

46) Ion Collection Efficiency in Ultra-High Dose Per Pulse Electron Beams (A.Bourgouin), FRPT2021 conference, December 2021.

45) Plastic Scintillator Under Ultra-High Dose Rate Electron Beam: Long Term Damages and Changes in Optical Response (B.Lessard), FRPT2021 conference, December 2021.

44) Vented Ionization Chambers for Ultra-High Dose Per Pulse Conditions (R.D.Kranzer), FRPT2021 conference, December 2021.

43) Realization and Characterization of Novel Diamond Detector Prototypes for Flash Therapy Application (G.V.Rinati), FRPT2021 conference, December 2021.

42) Monitoring a Flash Beam: for Preclinical Studies and Towards Clinical Applications (S.Heinrich), FRPT2021 conference, December 2021.

41) Faster Than Light: Can Scintillators Guide Electron Flash Experiments? (V.Vanreusel), FRPT2021 conference, December 2021.

40) Performance of a Probe Type Graphite Calorimeter (Aerrow) in Ultra High Dose Per Pulse Electron Beams (A.Bourgouin), FRPT2021 conference, December 2021.

39) Secondary Standard Dosimetry: Understanding the Ionization Chambers for the Future Ultra High Dose Rate Applications (J.P.Martin), FRPT2021 conference, December 2021.

38) Linearity of Diamond Detectors in Ultra High Dose Per Pulse Electron Beams (R.D.Kranzer), FRPT2021 conference, December 2021.

37) Ion Recombination Correction Factors and Benchmark of Detectors in a Very High Dose Rate Proton Scanning Beam (A.M.Leite), FRPT2021 conference, December 2021.

36) Multi Leaf Faraday Cup for Quality Assurance in Radiation Therapy With Electron and Ion Beams at Convetional and Ultra High Dose Rate (A.Schüller), FRPT2021 conference, December 2021.

35) Development and Test of a Small Portable Graphite Calorimeter for Use in Ultra High Dose Rate Particle Beams (R.A.Thomas), FRPT2021 conference, December 2021.

34) Calorimetry for Ultra-High-Dose-Rate Very High Energy Electron Beams (M.McManus), FRPT2021 conference, December 2021.

33) Irradiation of Luminescence Dosimeters in Stray Radiation Field in Laser-Driven Accelerators (A.Cimmino), FRPT2021 conference, December 2021.

32) Calorimetry Techniques for Absolute Dosimetry of Laser-Driven Ions Beams (S.McCallum), FRPT2021 conference, December 2021.

31) Dosimetry and Beam Delivery Arrangements for Single-Shot, Ultra-High Dose-Rate Radiobiology Experiments Employing Laser-Accelerated Ions (G.Milluzzo), FRPT2021 conference, December 2021.

30) Influence of Electron Beam Dose Rate and Pulse Structure on the Protecting Flash Effect Observed in Zebrafish Embryo (J.Pawelke), FRPT2021 conference, December 2021.

29) Metrology for Advanced Radiotherapy Using Particle Beams With Ultra-high
Pulse Dose: Test in Flash-like Electron Beam at Microtron MT 25
(I. Ambrožová), Applied Nuclear Physics Conference, September 2021.

28) Dosimetry for ultra-high dose rate radiotherapy with electron beams (A. Schüller), Strathclyde Virtual Workshop Ultra-high Dose Rate Radiotherapy, September 2021.

27) Dosimetry for FLASH radiotherapy with electron beams (A. Schüller), Joint Meeting of the ÖGMP, DGMP and SGSMP, September 2021. Video is here.

26) Towards primary and secondary standards for dosimetry in Flash radiotherapy (A. Bourgouin), Joint Meeting of the ÖGMP, DGMP and SGSMP, September 2021.

25) Clinical translation of FLASH radiation therapy: What has been done and the challenges still ahead (S.Heinrich), Strathclyde Virtual Workshop Ultra-high Dose Rate Radiotherapy, September 2021. Video is here (password: SVW:UHDRRT21).

24) Current state of the art and coming developments on dosimetry for FLASH
radiotherapy
(A. Schüller), FLASH radiation therapy in Brandenburg, Berlin and Northern Germany, DESY Zeuthen and virtual, August 2021.

23) Metrology for Advanced Radiotherapy using Particle Beams with Ultra-High Pulse Dose Rates (UHDpulse) (A. Cimmino), ELI Summer School 2021.

22) Absolute Dosimetry of Ultra-High Dose Rate Pulsed Electron Beams Using a Graphite Probe Calorimeter (F. Keszti), AAPM 63rd Annual Meeting, July 2021. Video of the presentation.

21) Overview of the EMPIR project UHDpulse “Metrology for advanced radiotherapy using particle beams with ultra high pulse dose rates” (A. Schüller), ESTRO European Particle Therapy Network (EPTN) WP2 Workshop “Ultra high dose rate dosimetry: what’s going on”, virtual meeting, May 2021.

20) Overview of the EMPIR project UHDpulse “Metrology for advanced radiotherapy using particle beams with ultra high pulse dose rates” (A. Schüller), AAPM COMMITTEE TREE, Task Group No. 359 – FLASH (ultra-high dose rate) radiation dosimetry, virtual meeting, April 2021.

19) Towards primary and secondary standards for dosimetry in Flash radiotherapy (A. Bourgouin), 2021 Virtual CIRMS Annual Meeting, April 2021. Video of the presentation. Meeting abstract.

18) The Joint Research Project UHDpulse – “Metrology for advanced radiotherapy using
particle beams with ultra-high pulse dose rates”
(A. Schüller), EURAMET Technical Committee for Ionising Radiation Contact Person Meeting 2021, February 2021.

17) The challenge of high dose rate for ionisation chambers (D. Poppinga), VHEE2020 Workshop Online, October 2020

16) Dosimetry of particle beams with ultra-high pulse dose rates (A. Subiel), VHEE2020 Workshop Online, October 2020

15) The challenges of Ultra high dose rate dosimetry for preclinical irradiation (C. Bailat), VHEE2020 Workshop Online, October 2020

14) Dosimetry of electron beams – challenges and possible solutions for VHEE and FLASH (A. Schüller), VHEE2020 Workshop Online, October 2020

13) UHDpulse – ein europäisches Forschungsprojekt zur Dosimetrie für neuartige Strahlentherapieansätze mit ultrahoher Pulsdosisleistung (A. Schüller), DGMP 2020 Online, September 2020

12) Calorimetry techniques for absolute dosimetry of proton beams with ultra-high pulse dose rates (F. Romano), PTCOG2020 Online, September 2020

11) Dosimetry for advanced radiotherapy approaches using particle beams with ultra-high pulse dose rates (UHPDR) in the EMPIR UHDpulse project (A. Subiel), PTCOG2020 Online, September 2020

10) Video: Investigation of a Simple Calorimeter Design for the Dosimetry of Ultra-High Pulse Dose Rate (FLASH) Electron Beams (A. Bourgouin), 2020 Joint AAPM | COMP Virtual Meeting, July 2020

9) Dosimetry of ultra-short high dose-per-pulse very high energy electron beams (M. McManus), 2020 Joint AAPM | COMP Virtual Meeting, July 2020

8) Dosimetry for proton irradiation of 3D cell models at ultra-high dose rate (G. Milluzzo), BLIN4: Beam Line and INstrumentation: Fourth Workshop, June 2020, online workshop

7) Calorimetry techniques for absolute dosimetry of laser-driven ions beams (S. McCallum), BLIN4: Beam Line and INstrumentation: Fourth Workshop, June 2020, online workshop

6) Introduction to FLASH-RT (C. Bailat), POLIMI online training course, May 2020, Italy. Video is also available here.

5) The Joint Research Project UHDpulse – “Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates” (A. Schüller), meeting “Transforming Radiotherapy in a Flash”, February 14, 2020, London, United Kingdom

4) Challenges in dosimetry of particle beams with ultra-high pulse dose rates (F. Romano), conference Mini- Micro- Nano- Dosimetry (MMND 2020) in conjunction with Innovation Technologies in Radiation Oncology (ITRO 2020), February 10-16, 2020, Wollongong, Australia. The corresponding paper is available here.

3) EMPIR project UHDpulse (Ch. Kottler), EURAMET Technical Committee for Ionising Radiation Contact Person Meeting 2020, January 28-30, 2020, Lisbon, Portugal

2) Dosimetry verification for FLASH radiotherapy (C. Bailat), ASTRO Annual Meeting, September 15-18, 2019, Chicago, USA

1) EMPIR project UHDpulse: “Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates”, (A. Schüller), International Conference on Medical Accelerators and Particle Therapy, September 4-6, 2019, Seville


Poster presentations

15) New Developments on SiC Dosimeters for Advanced Radiotherapies (C.Fleta), FRPT2021 conference, December 2021

14) Fluka Monte Carlo for Basic Dosimetric Studies of Uhpdr Electron Beams (A.Knyziak), FRPT2021 conference, December 2021

13) Characterization of OSL and TL Dosimeters with Data Collected at the MT25 Cyclic Electron Accelerator (A.Cimmino), FRPT2021 conference, December 2021

12) Monte Carlo Modelling of Pixel Clusters in Timepix Detectors Using the MCNP Code (J.Šolc), FRPT2021 conference, December 2021

11) Dosimetric Comparison Scheme Facilitating Multi Center FlashRT Pre Clinical Studies (C.Bailat), FRPT2021 conference, December 2021.

10) Establishment of a Flash Radiotherapy Facility at Npl and Dosimetry Study (A.Douralis), FRPT2021 conference, December 2021

9) Time-Stamped Measurements of Single Flash Pulses of Primary Electron Beams in Wide Dose Range and Micro Seconds Resolution With Miniaturized Minipix-TimePIX3-Flex Camera (C.Oancea), FRPT2021 conference, December 2021

8) Measurements of Scattered Radiation Produced in Electron Beams Using Minipix TimePIX3 Flex (C.Balan), FRPT2021 conference, December 2021

7) Towards primary and secondary standards for dosimetry in Flash radiotherapy (A. Bourgouin), International Metrology Congress, 7-9 September 2021, virtual conference. Poster mini presentation is here.

6) Characterization of stray radiation produced in FLASH electron beams using customized Minipix Timepix3 detectors (C.Balan), IWORID, June 2021.

5) In-water fast-time-sensitive measurements with Timepix3 detector for sensitive measurements with Timepix3 detector for dosimetry and and tracking characterization of stray radiation fields produced by FLASH proton beams (C.Oancea), PTCOG59, June 2021

4) The challenge of dosimetry in Flash Radiotherapy (F. Gomez), IFIMED de Física Médica, 14-15 December 2020, virtual conference

3) Study of OSL Dosimeters in Ultra-High Pulse Dose Rates Particle Beams at ELI Beamlines Laser Facility (A. Cimmino), ELI Summer School 2020, August 2020, Hungary

2) Dosimetry for advanced radiotherapy approaches using particle beams with ultra-high pulse dose rates in the EMPIR UHDpulse project (A. Subiel), 2020 Joint AAPM | COMP Virtual Meeting, July 2020

1) Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates (in Czech; J. Šolc), XLI. Days of Radiation Protection, November 4-8, 2019, Mikulov, Czech Republic


Other publications

6-39) Abstracts from the FRPT2021 conference, Physica Medica, February 2022.

5) S. McCallum, Assessment of the reliability of deconvolution procedures for RCF spectroscopy of laser-driven ion beams, Journal of Instrumentation, February 2022.

4) A. Bourgouin, Towards primary and secondary standards for dosimetry in Flash radiotherapy, abstract for 2021 Virtual CIRMS Annual Meeting, April 2021. Other material: video and presentation.

3) A. Schüller et al., FLASH Radiotherapy and Particle Therapy Conference (FRPT 2021): a short article in the OMA Express – the Newsletter of the Optimization of Medical Accelerators Project, page 11, March 2021 (pdf)

2) S. Motta, Characterization of OSL dosimeters for radiation protection at ELI Beamlines laser facility, Master’s thesis, Politecnico di Milano, Milan, Italy, April 2020

1) A. Schüller et al., UHDpulse: A new European research project: a short article in the OMA Express – the Newsletter of the Optimization of Medical Accelerators Project, page 12, February 2020 (version for web is here)